Clinical GeneticsLaajuus (5 cr)

Objective

The student
• is able to explain the structure and functions of the human genome and regulation of these functions, as well as the links of these factors to disease mechanisms
• understands the principles of the most common molecular genetics and cytogenetics methods, and the basics and key applications of recombinant DNA technology
• is able to explain the basic concepts of genetics
• knows the differences in DNA and RNA expression, the formation of chromosomes and the most common mutation types
• is able to explain the most hereditary patterns and define ethical problems related to molecular biology and gene technology tests
• knows the sample types used in testing including their quality requirements, and is able to explain the main principles of new molecular biology methods
• is able to carry out molecular biology and cytogenetic examinations and to grow cells
• understands the principles of quality control and occupational and patient safety and complies with them when working.

Content

• Basic concepts of genetics
• Human genome, chromosomes, genetic structure and the most common mutation types
• DNA extraction and factors affecting it
• DNA multiplication methods
• Commonest methods used in genetics
• Basics of cell culture and the use of grown cells in diagnostics
• Cancer genetics and research methods
• Aseptic work and contaminations
• Ethics in molecular biology and gene technology

Theory 2.5 ECTS
Practice 2.5 ECTS

Qualifications

Anatomy, Physiology and Pathophysiology, Basic Laboratory Work, Chemistry, Cell Biology,

Assessment criteria, satisfactory (1)

For assessment criteria, see the attachment.
The assessment criteria for advanced level are applied.