Organic ChemistryLaajuus (6 ECTS)

Objective

After completion of this course the student understands the hybridization of the electron orbitals of a carbon atom and its significance with respect to the properties of different organic compounds. In addition, the student understands the most common organic reaction types and mechanisms, recognizes different functional groups and understands their effect on the behavior of the compound. The student also understands the principles and knows the fields of application of the following most common analytical techniques used in organic chemistry:
- recrystallisation
- (vacuum) distillation
- chromatography (TLC, HPLC, GC)
- polarimetry
- refractometry
- spectroscopy (UV and FTIR-spectroscopy)
In addition, the student knows and understands how to influence the steps, rates and yield of an organic reaction.

Detailed understanding of the reaction mechanisms in organic synthesis reactions and of the principles of analytical techniques applied in organic chemistry.
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After completion of this course the student is able to give systematic names based on IUPAC rules to organic compounds of intermediate level, and to sketch structural formulae for organic compounds on the basis of a given systematic name. In addition, he knows which compounds can be formed from a given compound by means of oxidation or reduction, and he is able to propose suitable reagents for the oxidation and the reduction reactions. He is also able to use glassware, vessels and tools commonly used in practical organic chemistry. He can also apply the important precautions with regard to safety in a laboratory for organic chemistry as well as the ways how to dispose of organic waste. In addition, the student is able to plan and assemble experimental set-ups commonly used in organic synthesis and analysis. He can also qualitatively assess possible sources of error in practical laboratory experiments and is able to use the following equipment:
- a heating device for the determination of melting point
- refractometer
- polarimeter
- FTIR spectrophotometer

Content

Identification of organic compounds: nomenclature and different formulae. Isomerism. The hybridization of the orbitals of a carbon atom and the different types of bonds in organic compounds. The oxidation state of organic compounds, functional groups and their reactivity, especially towards water. The most important reaction types and mechanisms. Laboratory-scale synthesis and analysis in organic chemistry, as well as the tools, equipment, methods and techniques required.
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Specific reactions and reaction mechanisms of compound types and individual compounds. Optical activity. Detailed understanding of the mechanisms of organic synthesis reactions.

Further information

Class room teaching: 63 h
Laboratory exercises: 35 h
Exam: 6 h
Student individual workload (student workload analysis carried out 1/06): 90 h
Total: 194 h
Follow-up of the student workload analysis performed: -