Pathology and Pharmacology (10 ECTS)

Location and time

Spring semester 2022 in the campus of Myllypuro/online via ZOOM.

Materials

Lecture materials

Books
- Lääketieteellinen farmakologia ja toksikologia (A Finnish textbook of medical pharmacology and toxicology); Heikki Ruskoaho, Jukka Hakkola, Risto Huupponen, Anu Kantele, Esa R. Korpi, Eeva Moilanen, Petteri Piepponen, Eriika Savontaus, Olli Tenhunen, Kirsi Vähäkangas (ed.); 5th edition 2019; ISBN: 978-952-360-011-9.
- Clinical Ocular Pharmacology, 5th Edition by Jimmy D. Bartlett OD DOS ScD (Author), Siret D. Jaanus PhD LHD (Author), Butterworth Heinemann Elsevier, 2008, ISBN-13: 978-0750675765 ISBN-10: 0750675764.
- Patologia (A Finnish textbook of pathology); Markus Mäkinen, Olli Carpén, Veli-Matti Kosma, Veli-Pekka Lehto, Timo Paavonen, Frej Stenbäck (ed.); 1st edition 2012; ISBN: 978-951-656-184-7.
- Pathophysiology, The biological basis for disease in adults and children, 8th Edition by Kathryn L. McCance MS PhD (Author), Sue E. Huether MS PhD (Author), Valentina L. Brashers MD FACP FNAP (Section Editor), Neal S. Rote PhD (Section Editor), Elsevier, 2019, ISBN: 978-0-323-58347-3.

Employer connections

No practical lectures

Exam schedules

Pathology written examination 24.02.2022; Retake 1: 18.03.2022; Retake 2: 05.04.2022

Pharmacology written examination 20.04.2022; Retake 1: 30.05.2022; Retake 2: xx.xx.2022

Completion alternatives

No

Evaluation methods and criteria

Written examinations
- pathology
- pharmacology

Pair work seminar (written+ oral presentation) ;returned, approved + oral presentation
To pass the course, the students are expected to attend the lectures.

Student workload

Pharmacology 5 ECTS
Pathology 5 ECTS

Teaching methods

Lectures
Pair work seminar
- written work
- oral presentation

Further information

All the material given during the studies is not to be shared with other or third parts and is only allowed to be used for the students own learning purposes.


In case a student has a decision on special support arrangements affecting the course the student needs to contact the teacher in charge right after enrollment period.


Detailed content, theory:
Pathology:
Inflammation and repair

Infectious diseases
o Viral diseases
o Bacterial diseases
o Fungal diseases
o Parasitic diseases

Neurologic diseases and the eye
o Headache
o Multiple sclerosis
o Brain tumors
o Intracranial pressure
o Neuromuscular diseases

Cardiovascular diseases and the eye
o Hypertension
o Atherosclerosis
o Carotis stenosis
o Aneurysma
o Stroke

Blood diseases and the eye
o Anemia
o Leucemia
o Lymphoma

Endocrine diseases and the eye
o Diabetes
o Grave’s disease and endocrine orbitopathy

Nutritional disorders
o Malabsorption
o Alcoholism
o Vitamin deficiencies

Rheumatoid disorders, Vasculitis and Collagenosis
o Rheumatoid polyarthritis
o Morbus Bechterew
o Reiters Syndrome
o Sjogren Syndrom
o Giant cell arteriitis

Tumours
o Brain tumours and vision
o Ocular metastasis of primary tumours

Congential and hereditary conditions
o Symptoms and signs of common genetic disorders
Symptoms and signs of common congenital disorders (foetal alcohol syndrome, rubella, syphilis, toxoplasmosis)

GENERAL PHARMACOLOGY:
• Pharmacokinetics
• Pharmacodynamics

• Drugs acting on the autonomic nervous system
-Cholinergic agonists and antagonists
-Adrenergic agonists and antagonists

• Analgesics and local anaesthetics

• Antipyretics and anti-inflammatory drugs

• Antibiotics

• Antiviral drugs

• Antiallergic drugs

• Drugs affecting respiratory and cardiovascular system

• Antiseptics, disinfectants, preservatives

• Common systemic side effects of medications

OCULAR PHARMACOLOGY:
General Principles
o Factors affecting ocular drug bioavailability
o Routes of ocular drug administration

Autonomic Drugs
o Functional concepts and ocular receptor types
o Ocular cholinergic agents
o Ocular adrenergic agents

Local anaesthetics
o Properties of topical ocular anaesthetics (non-injectable)
Antihistamines

Anti-inflammatory agents
o Steroid
o Non-steroids (including mast cell stabilizers)

Chemotherapeutic agents
o Antimicrobials
o Antivirals
o Antifungals

Dyes
o Topical diagnostic agents
o Oral and intravenous agents

Hyperosmotic agents
o Topical diagnostic agents

Lubricants and tear substitutes

Preparations used with contact lenses

Toxicology
o Ocular effects from topical ocular drug administration
o Ocular effects from systemic drug administration
o Systemic effects from ocular drug administration

Evaluation scale

0-5

Assessment criteria, satisfactory (1)

The student is able to:
- display learning in professional knowledge and core content in the field
- search information from a variety of sources
- work in various duties in a variety of operating environments
- show that he has achieved the targets for core competence
- display learning in the key safety practices in the field
- act according to ethical principles
- to contribute his learning for the benefit of a group or project

Assessment criteria, good (3)

The student is able to:
- use concepts and knowledge in his field systematically
- find information and assess and use information sources with a critical eye
- apply professional information in professional assignments
- apply professional expertise in various work assignments
- act independently and responsibly in professional contexts
- plan operations with safety in mind
- act according to professional ethics
- act purposefully in working groups and projects

Assessment criteria, excellent (5)

The student is able to:
- use concepts and knowledge in his field professionally
- argue the use of his sources - argue a course of action on the basis of research information or findings
- operate in a range of duties and work situations, also in international contexts
- to act in a way that is customeroriented and displays entrepreneurial spirit
- to act responsibly, taking safety issues into consideration
- argue his choices on the basis of professional ethics
- organise and manage the operation of a group and project

Assessment criteria, approved/failed

The student is able to:
- display learning in professional knowledge and core content in the field
- search information from a variety of sources
- work in various duties in a variety of operating environments
- show that he has achieved the targets for core competence
- display learning in the key safety practices in the field
- act according to ethical principles
- to contribute his learning for the benefit of a group or project

Further information

All the material given during the studies is not to be shared with other or third parts and is only allowed to be used for the students own learning purposes.


In case a student has a decision on special support arrangements affecting the course the student needs to contact the teacher in charge right after enrollment period.


Detailed content, theory:
Pathology:
Inflammation and repair

Infectious diseases
o Viral diseases
o Bacterial diseases
o Fungal diseases
o Parasitic diseases

Neurologic diseases and the eye
o Headache
o Multiple sclerosis
o Brain tumors
o Intracranial pressure
o Neuromuscular diseases

Cardiovascular diseases and the eye
o Hypertension
o Atherosclerosis
o Carotis stenosis
o Aneurysma
o Stroke

Blood diseases and the eye
o Anemia
o Leucemia
o Lymphoma

Endocrine diseases and the eye
o Diabetes
o Grave’s disease and endocrine orbitopathy

Nutritional disorders
o Malabsorption
o Alcoholism
o Vitamin deficiencies

Rheumatoid disorders, Vasculitis and Collagenosis
o Rheumatoid polyarthritis
o Morbus Bechterew
o Reiters Syndrome
o Sjogren Syndrom
o Giant cell arteriitis

Tumours
o Brain tumours and vision
o Ocular metastasis of primary tumours

Congential and hereditary conditions
o Symptoms and signs of common genetic disorders
Symptoms and signs of common congenital disorders (foetal alcohol syndrome, rubella, syphilis, toxoplasmosis)

GENERAL PHARMACOLOGY:
• Pharmacokinetics
• Pharmacodynamics

• Drugs acting on the autonomic nervous system
-Cholinergic agonists and antagonists
-Adrenergic agonists and antagonists

• Analgesics and local anaesthetics

• Antipyretics and anti-inflammatory drugs

• Antibiotics

• Antiviral drugs

• Antiallergic drugs

• Drugs affecting respiratory and cardiovascular system

• Antiseptics, disinfectants, preservatives

• Common systemic side effects of medications

OCULAR PHARMACOLOGY:
General Principles
o Factors affecting ocular drug bioavailability
o Routes of ocular drug administration

Autonomic Drugs
o Functional concepts and ocular receptor types
o Ocular cholinergic agents
o Ocular adrenergic agents

Local anaesthetics
o Properties of topical ocular anaesthetics (non-injectable)
Antihistamines

Anti-inflammatory agents
o Steroid
o Non-steroids (including mast cell stabilizers)

Chemotherapeutic agents
o Antimicrobials
o Antivirals
o Antifungals

Dyes
o Topical diagnostic agents
o Oral and intravenous agents

Hyperosmotic agents
o Topical diagnostic agents

Lubricants and tear substitutes

Preparations used with contact lenses

Toxicology
o Ocular effects from topical ocular drug administration
o Ocular effects from systemic drug administration
o Systemic effects from ocular drug administration